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Left frontal hypoactivation in depression
Journal of Abnormal Psychology
Format: Journal Article
Publication Year: n/a
Pages: 535-545
Source ID: shanti-sources-22653
Zotero Collections: Contexts of Contemplation Project
Abstract: Baseline resting electroencephalogram activity was recorded with 3 different reference montages from 15 clinically depressed and 13 control subjects. Power in all frequency bands was extracted by fast Fourier transformation. There was a significant Group X Hemisphere interaction in the mid-frontal region, for the alpha band power only. Depressed subjects had less left-sided activation (i.e., more alpha activity) than did normal control subjects. This pattern of diminished left-sided frontal activation is interpreted as indicating a deficit in approach mechanisms in depressed subjects.