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There is a growing interest in studies that document the relationship between science and medicine - as ideas, practices, technologies and outcomes - across cultural, national, geographic terrain. Tibetan medicine is not only known as a scholarly medical tradition among other Asian medical systems, with many centuries of technological, clinical, and pharmacological innovation; it also survives today as a complex medical resource across many Asian nations - from India and Bhutan to Mongolia, Tibet (TAR) and China, Buryatia - as well as in Western Europe and the Americas. The contributions to this volume explore, in equal measure, the impacts of western science and biomedicine on Tibetan grounds - i.e., among Tibetans across China, the Himalaya and exile communities as well as in relation to globalized Tibetan medicine - and the ways that local practices change how such “science” gets done, and how this continually hybridized medical knowledge is transmitted and put into practice. As such, this volume contributes to explorations into the bi-directional flows of medical knowledge and practice.